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This is completely normal and is not a sign that anything is wrong or that the medicine is not working

It's important to note that tirzepatide is not indicated for the treatment of type 1 diabetes or diabetic ketoacidosis

The dual-agonist mechanism produces greater suppression of energy intake than single-pathway activation

However, this is an essential tenet of all long-term diabetes modelling and arguably represents the best source of evidence for decision-making in the absence of long-term clinical trial data

Glucagon-like peptide-1 (GLP-1) analogs: recent advances, new possibilities, and therapeutic implications